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A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions

The effects of genotoxic stress can be mediated by activation of the Ataxia Telangiectasia Mutated (ATM) kinase, under both DNA damage-dependent (including ionizing radiation), and independent (including hypoxic stress) conditions. ATM activation is complex, and primarily mediated by the lysine acet...

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Detalles Bibliográficos
Autores principales: Likhatcheva, Maria, Gieling, Roben G., Brown, James A. L., Demonacos, Constantinos, Williams, Kaye J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491615/
https://www.ncbi.nlm.nih.gov/pubmed/34621741
http://dx.doi.org/10.3389/fcell.2021.720194