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Striatal histamine mechanism in the pathogenesis of restless legs syndrome

STUDY OBJECTIVES: Restless legs syndrome (RLS) has been hypothesized to be generated by abnormal striatal dopamine transmission. Dopaminergic drugs are effective for the treatment of RLS. However, long-term use of dopaminergic drugs causes adverse effects. We used iron-deficient (ID) and iron-replac...

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Detalles Bibliográficos
Autores principales: Lai, Yuan-Yang, Hsieh, Kung-Chiao, Cheng, Yu-Hsuan, Chew, Keng-Tee, Nguyen, Darian, Ramanathan, Lalini, Siegel, Jerome M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491621/
https://www.ncbi.nlm.nih.gov/pubmed/31671173
http://dx.doi.org/10.1093/sleep/zsz223