Direct C(sp(3))–H allylation of 2-alkylpyridines with Morita–Baylis–Hillman carbonates via a tandem nucleophilic substitution/aza-Cope rearrangement

A base- and catalyst-free C(sp(3))–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem S(N)2’ type nucleophilic substitution followed by an aza-Cope rearrangement. Various alkyl substituents o...

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Detalles Bibliográficos
Autores principales: Wang, Siyu, Zheng, Lianyou, Wang, Shutao, Ning, Shulin, Zhang, Zhuoqi, Xiang, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491709/
https://www.ncbi.nlm.nih.gov/pubmed/34646399
http://dx.doi.org/10.3762/bjoc.17.167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491709/
https://www.ncbi.nlm.nih.gov/pubmed/34646399
http://dx.doi.org/10.3762/bjoc.17.167

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