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Direct C(sp(3))–H allylation of 2-alkylpyridines with Morita–Baylis–Hillman carbonates via a tandem nucleophilic substitution/aza-Cope rearrangement

A base- and catalyst-free C(sp(3))–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem S(N)2’ type nucleophilic substitution followed by an aza-Cope rearrangement. Various alkyl substituents o...

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Detalles Bibliográficos
Autores principales:	Wang, Siyu, Zheng, Lianyou, Wang, Shutao, Ning, Shulin, Zhang, Zhuoqi, Xiang, Jinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2021
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491709/ https://www.ncbi.nlm.nih.gov/pubmed/34646399 http://dx.doi.org/10.3762/bjoc.17.167

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