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Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine

The aim of this article was to design a self-emulsifying drug delivery system (SEDDS) of loaded cepharanthine (CEP) to improve the oral bioavailability in rats. Based on the solubility determination and pseudo-ternary phase diagram, isopropyl palmitate (IPP) was chosen as the oil phase. Meanwhile, C...

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Detalles Bibliográficos
Autores principales: Yang, Xinggang, Gao, Pan, Jiang, Zhujun, Luo, Qiao, Mu, Chengqiao, Cui, Mengsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491757/
https://www.ncbi.nlm.nih.gov/pubmed/34611770
http://dx.doi.org/10.1208/s12249-021-02085-9