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Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
The aim of this article was to design a self-emulsifying drug delivery system (SEDDS) of loaded cepharanthine (CEP) to improve the oral bioavailability in rats. Based on the solubility determination and pseudo-ternary phase diagram, isopropyl palmitate (IPP) was chosen as the oil phase. Meanwhile, C...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491757/ https://www.ncbi.nlm.nih.gov/pubmed/34611770 http://dx.doi.org/10.1208/s12249-021-02085-9 |