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SARS-CoV-2 spike-specific memory B cells express markers of durable immunity after non-severe COVID-19 but not after severe disease

SARS-CoV-2 infection elicits a robust B cell response, resulting in the generation of long-lived plasma cells and memory B cells. Here, we aimed to determine the effect of COVID-19 severity on the memory B cell response and characterize changes in the memory B cell compartment between recovery and f...

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Detalles Bibliográficos
Autores principales: Reyes, Raphael A., Clarke, Kathleen, Gonzales, S. Jake, Cantwell, Angelene M., Garza, Rolando, Catano, Gabriel, Tragus, Robin E., Patterson, Thomas F., Bol, Sebastiaan, Bunnik, Evelien M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491845/
https://www.ncbi.nlm.nih.gov/pubmed/34611662
http://dx.doi.org/10.1101/2021.09.24.461732