Anti-PF4 VITT antibodies are oligoclonal and variably inhibited by heparin

BACKGROUND: COVID-19 vaccines have been associated with a rare thrombotic and thrombocytopenic reaction, Vaccine-induced immune thrombotic thrombocytopenia (VITT) characterized by platelet-activating anti-PF4 antibodies. This study sought to assess clonality of VITT antibodies and evaluate their cha...

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Detalles Bibliográficos
Autores principales: Singh, B, Kanack, A, Bayas, A, George, G, Abou-Ismail, MY, Kohlhagen, M, Christ, M, Naumann, M, Moser, K, Smock, K, Grazioli, A, Murray, D, Padmanabhan, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491860/
https://www.ncbi.nlm.nih.gov/pubmed/34611669
http://dx.doi.org/10.1101/2021.09.23.21263047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491860/
https://www.ncbi.nlm.nih.gov/pubmed/34611669
http://dx.doi.org/10.1101/2021.09.23.21263047

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