Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir

Rapid repurposing of existing drugs as new therapeutics for COVID-19 has been an important strategy in the management of disease severity during the ongoing SARS-CoV-2 pandemic. Here, we used high-throughput docking to screen 6000 compounds within the DrugBank library for their potential to bind and...

Descripción completa

Detalles Bibliográficos
Autores principales: Pohl, Marie O., Busnadiego, Idoia, Marrafino, Francesco, Wiedmer, Lars, Hunziker, Annika, Fernbach, Sonja, Glas, Irina, Moroz-Omori, Elena V., Hale, Benjamin G., Caflisch, Amedeo, Stertz, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491895/
https://www.ncbi.nlm.nih.gov/pubmed/34319869
http://dx.doi.org/10.1099/jgv.0.001625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491895/
https://www.ncbi.nlm.nih.gov/pubmed/34319869
http://dx.doi.org/10.1099/jgv.0.001625

Ejemplares similares