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Experimental and computational investigation of enzyme functional annotations uncovers misannotation in the EC 1.1.3.15 enzyme class

Only a small fraction of genes deposited to databases have been experimentally characterised. The majority of proteins have their function assigned automatically, which can result in erroneous annotations. The reliability of current annotations in public databases is largely unknown; experimental at...

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Detalles Bibliográficos
Autores principales: Rembeza, Elzbieta, Engqvist, Martin K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491902/
https://www.ncbi.nlm.nih.gov/pubmed/34555022
http://dx.doi.org/10.1371/journal.pcbi.1009446