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The mechanism of complex formation between calmodulin and voltage gated calcium channels revealed by molecular dynamics
Calmodulin, a ubiquitous eukaryotic calcium sensor responsible for the regulation of many fundamental cellular processes, is a highly flexible protein and exhibits an unusually wide range of conformations. Furthermore, CaM is known to interact with more than 300 cellular targets. Molecular dynamics...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491939/ https://www.ncbi.nlm.nih.gov/pubmed/34610038 http://dx.doi.org/10.1371/journal.pone.0258112 |