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The mechanism of complex formation between calmodulin and voltage gated calcium channels revealed by molecular dynamics

Calmodulin, a ubiquitous eukaryotic calcium sensor responsible for the regulation of many fundamental cellular processes, is a highly flexible protein and exhibits an unusually wide range of conformations. Furthermore, CaM is known to interact with more than 300 cellular targets. Molecular dynamics...

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Detalles Bibliográficos
Autores principales: Yaduvanshi, Shivani, Ero, Rya, Kumar, Veerendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491939/
https://www.ncbi.nlm.nih.gov/pubmed/34610038
http://dx.doi.org/10.1371/journal.pone.0258112