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An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia

This study aimed to investigate DNA methylation levels in patients undergoing major breast surgery under opioid-based general anesthesia. Blood samples were collected from eleven enrolled patients, before, during and after anesthesia. PBMC were isolated and global DNA methylation levels as well as D...

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Detalles Bibliográficos
Autores principales: Caputi, Francesca Felicia, Carboni, Lucia, Rullo, Laura, Alessandrini, Irene, Balzani, Eleonora, Melotti, Rita Maria, Romualdi, Patrizia, Candeletti, Sanzio, Fanelli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491974/
https://www.ncbi.nlm.nih.gov/pubmed/34621169
http://dx.doi.org/10.3389/fphar.2021.733577