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Understanding mutation hotspots for the SARS-CoV-2 spike protein using Shannon Entropy and K-means clustering

The SARS-CoV-2 virus like many other viruses has transformed in a continual manner to give rise to new variants by means of mutations commonly through substitutions and indels. These mutations in some cases can give the virus a survival advantage making the mutants dangerous. In general, laboratory...

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Detalles Bibliográficos
Autores principales: Mullick, Baishali, Magar, Rishikesh, Jhunjhunwala, Aastha, Barati Farimani, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492016/
https://www.ncbi.nlm.nih.gov/pubmed/34655896
http://dx.doi.org/10.1016/j.compbiomed.2021.104915