Local adaptation and archaic introgression shape global diversity at human structural variant loci

Large genomic insertions and deletions are a potent source of functional variation, but are challenging to resolve with short-read sequencing, limiting knowledge of the role of such structural variants (SVs) in human evolution. Here, we used a graph-based method to genotype long-read-discovered SVs...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Stephanie M, Sherman, Rachel M, Taylor, Dylan J, Nair, Divya R, Bortvin, Andrew N, Schatz, Michael C, McCoy, Rajiv C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492059/
https://www.ncbi.nlm.nih.gov/pubmed/34528508
http://dx.doi.org/10.7554/eLife.67615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492059/
https://www.ncbi.nlm.nih.gov/pubmed/34528508
http://dx.doi.org/10.7554/eLife.67615

Ejemplares similares