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Visualizing formation of the active site in the mitochondrial ribosome

Ribosome assembly is an essential and conserved process that is regulated at each step by specific factors. Using cryo-electron microscopy (cryo-EM), we visualize the formation of the conserved peptidyl transferase center (PTC) of the human mitochondrial ribosome. The conserved GTPase GTPBP7 regulat...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Viswanathan, Desai, Nirupa, Burton, Nicholas O, Yang, Hanting, Price, Jon, Miska, Eric A, Ramakrishnan, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492066/
https://www.ncbi.nlm.nih.gov/pubmed/34609277
http://dx.doi.org/10.7554/eLife.68806