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Structural characterization of NrnC identifies unifying features of dinucleases

RNA degradation is fundamental for cellular homeostasis. The process is carried out by various classes of endolytic and exolytic enzymes that together degrade an RNA polymer to mono-ribonucleotides. Within the exoribonucleases, nano-RNases play a unique role as they act on the smallest breakdown pro...

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Detalles Bibliográficos
Autores principales: Lormand, Justin D, Kim, Soo-Kyoung, Walters-Marrah, George A, Brownfield, Bryce A, Fromme, J Christopher, Winkler, Wade C, Goodson, Jonathan R, Lee, Vincent T, Sondermann, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492067/
https://www.ncbi.nlm.nih.gov/pubmed/34533457
http://dx.doi.org/10.7554/eLife.70146