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A Double-blind, Randomized Trial to Evaluate Miltefosine and Topical Granulocyte Macrophage Colony-stimulating Factor in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis in Brazil

BACKGROUND: The treatment of cutaneous leishmaniasis (CL) in Brazil using pentavalent antimony (Sbv) is associated with a high rate of failure. Miltefosine has proven efficacy for CL caused by L. braziliensis, with a cure rate (CR) of 75%. A combined treatment with granulocyte macrophage colony-stim...

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Detalles Bibliográficos
Autores principales: Machado, Paulo R L, Prates, Fernanda V O, Boaventura, Viviane, Lago, Tainã, Guimarães, Luiz H, Schriefer, Albert, Corte, Temis W F, Penna, Gerson, Barral, Aldina, Barral-Netto, Manoel, Carvalho, Edgar M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492114/
https://www.ncbi.nlm.nih.gov/pubmed/32894278
http://dx.doi.org/10.1093/cid/ciaa1337