Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis

The epidermal growth factor receptor (EGFR) is an essential driver of oncogenic signalling, and EGFR inhibitors are some of the earliest examples of successful targeted therapies in multiple types of cancer. The tractability of EGFR as a therapeutic target is overshadowed by the inevitable drug resi...

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Detalles Bibliográficos
Autores principales: Kadry, Yasmin A., Lee, Jia-Ying, Witze, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492172/
https://www.ncbi.nlm.nih.gov/pubmed/34610265
http://dx.doi.org/10.1098/rsob.210033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492172/
https://www.ncbi.nlm.nih.gov/pubmed/34610265
http://dx.doi.org/10.1098/rsob.210033

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