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Novel generic models for differentiating stem cells reveal oscillatory mechanisms

Understanding cell fate selection remains a central challenge in developmental biology. We present a class of simple yet biologically motivated mathematical models for cell differentiation that generically generate oscillations and hence suggest alternatives to the standard framework based on Waddin...

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Detalles Bibliográficos
Autores principales: Farjami, Saeed, Camargo Sosa, Karen, Dawes, Jonathan H. P., Kelsh, Robert N., Rocco, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492175/
https://www.ncbi.nlm.nih.gov/pubmed/34610261
http://dx.doi.org/10.1098/rsif.2021.0442