BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ

RNA polymerase II (Pol II)-dependent transcription in stimulus-inducible genes requires topoisomerase IIβ (TOP2B)-mediated DNA strand break and the activation of DNA damage response signalling in humans. Here, we report a novel function of the breast cancer 1 (BRCA1)-BRCA1-associated ring domain 1 (...

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Detalles Bibliográficos
Autores principales: Bunch, Heeyoun, Jeong, Jaehyeon, Kang, Keunsoo, Jo, Doo Sin, Cong, Anh T. Q., Kim, Deukyeong, Kim, Donguk, Cho, Dong-Hyung, Lee, You Mie, Chen, Benjamin P. C., Schellenberg, Matthew J., Calderwood, Stuart K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492178/
https://www.ncbi.nlm.nih.gov/pubmed/34610268
http://dx.doi.org/10.1098/rsob.210221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492178/
https://www.ncbi.nlm.nih.gov/pubmed/34610268
http://dx.doi.org/10.1098/rsob.210221

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