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Distinguishing between models of mammalian gene expression: telegraph-like models versus mechanistic models
Two-state models (telegraph-like models) have a successful history of predicting distributions of cellular and nascent mRNA numbers that can well fit experimental data. These models exclude key rate limiting steps, and hence it is unclear why they are able to accurately predict the number distributi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492181/ https://www.ncbi.nlm.nih.gov/pubmed/34610262 http://dx.doi.org/10.1098/rsif.2021.0510 |