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Study on the Mechanism of miR-34a Affecting the Proliferation, Migration, and Invasion of Human Keloid Fibroblasts by Regulating the Expression of SATB1

OBJECTIVES: To explore the effect and mechanism of miR-34a on the proliferation, migration, and invasion of keloid fibroblasts (KFB). METHODS: Isolate and culture KFB and normal skin fibroblast (NFB), detect the mRNA expression levels of miR-34a and integrin β5 (SATB1) in KFB and NFB by RT-qPCR, and...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Shi, Xiufang, Wang, Meng, Chen, Huaxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492263/
https://www.ncbi.nlm.nih.gov/pubmed/34621503
http://dx.doi.org/10.1155/2021/8741512