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Fibroblast-specific IKK-β deficiency ameliorates angiotensin II–induced adverse cardiac remodeling in mice

Cardiac inflammation and fibrosis contribute significantly to hypertension-related adverse cardiac remodeling. IκB kinase β (IKK-β), a central coordinator of inflammation through activation of NF-κB, has been demonstrated as a key molecular link between inflammation and cardiovascular disease. Howev...

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Detalles Bibliográficos
Autores principales: Lu, Weiwei, Meng, Zhaojie, Hernandez, Rebecca, Zhou, Changcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492299/
https://www.ncbi.nlm.nih.gov/pubmed/34324438
http://dx.doi.org/10.1172/jci.insight.150161