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Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis

Oligoarticular juvenile idiopathic arthritis (oligo JIA) is the most common form of chronic inflammatory arthritis in children, yet the cause of this disease remains unknown. To understand immune responses in oligo JIA, we immunophenotyped synovial fluid T cells with flow cytometry, bulk RNA-Seq, si...

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Detalles Bibliográficos
Autores principales: Julé, Amélie M., Hoyt, Kacie J., Wei, Kevin, Gutierrez-Arcelus, Maria, Taylor, Maria L., Ng, Julie, Lederer, James A., Case, Siobhan M., Chang, Margaret H., Cohen, Ezra M., Dedeoglu, Fatma, Hazen, Melissa M., Hausmann, Jonathan S., Halyabar, Olha, Janssen, Erin, Lo, Jeffrey, Lo, Mindy S., Meidan, Esra, Roberts, Jordan E., Son, Mary Beth F., Sundel, Robert P., Lee, Pui Y., Chatila, Talal, Nigrovic, Peter A., Henderson, Lauren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492302/
https://www.ncbi.nlm.nih.gov/pubmed/34403374
http://dx.doi.org/10.1172/jci.insight.149185