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GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization

The migrating keratinocyte wound front is required for skin wound closure. Despite significant advances in wound healing research, we do not fully understand the molecular mechanisms that orchestrate collective keratinocyte migration. Here, we show that, in the wound front, the epidermal transcripti...

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Detalles Bibliográficos
Autores principales: Kashgari, Ghaidaa, Venkatesh, Sanan, Refuerzo, Samuel, Pham, Brandon, Bayat, Anita, Klein, Rachel Herndon, Ramos, Raul, Ta, Albert Paul, Plikus, Maksim V., Wang, Ping H., Andersen, Bogi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492311/
https://www.ncbi.nlm.nih.gov/pubmed/34494554
http://dx.doi.org/10.1172/jci.insight.142577