Cargando…
Lipin 1 modulates mRNA splicing during fasting adaptation in liver
Lipin 1 regulates cellular lipid homeostasis through roles in glycerolipid synthesis (through phosphatidic acid phosphatase activity) and transcriptional coactivation. Lipin 1–deficient individuals exhibit episodic disease symptoms that are triggered by metabolic stress, such as stress caused by pro...
Autores principales: | Wang, Huan, Chan, Tracey W., Vashisht, Ajay A., Drew, Brian G., Calkin, Anna C., Harris, Thurl E., Wohlschlegel, James A., Xiao, Xinshu, Reue, Karen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492312/ https://www.ncbi.nlm.nih.gov/pubmed/34494556 http://dx.doi.org/10.1172/jci.insight.150114 |
Ejemplares similares
-
Crystal structure of a lipin/Pah phosphatidic acid phosphatase
por: Khayyo, Valerie I., et al.
Publicado: (2020) -
Publisher Correction: Crystal structure of a lipin/Pah phosphatidic acid phosphatase
por: Khayyo, Valerie I., et al.
Publicado: (2020) -
The middle lipin domain adopts a membrane-binding dimeric protein fold
por: Gu, Weijing, et al.
Publicado: (2021) -
Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle
por: Castro, Victoria, et al.
Publicado: (2019) -
Role of lipins in cardiovascular diseases
por: Ding, Zerui, et al.
Publicado: (2023)