Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS

The prevalence of hypertension is increasing globally, while strategies for prevention and treatment of hypertension remain limited. FG-4592 (Roxadustat) is a potentially novel, orally active small-molecule hypoxia-inducible factor (HIF) stabilizer and is being used clinically to treat chronic kidne...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jing, Wang, Shuqin, Shi, Wei, Zhou, Wei, Niu, Yujia, Huang, Songming, Zhang, Yue, Zhang, Aihua, Jia, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492313/
https://www.ncbi.nlm.nih.gov/pubmed/34403364
http://dx.doi.org/10.1172/jci.insight.133690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492313/
https://www.ncbi.nlm.nih.gov/pubmed/34403364
http://dx.doi.org/10.1172/jci.insight.133690

Ejemplares similares