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CD138 expression is a molecular signature but not a developmental requirement for RORγt(+) NKT17 cells

Invariant NKT (iNKT) cells are potent immunomodulatory cells that acquire effector function during their development in the thymus. IL-17–producing iNKT cells are commonly referred to as NKT17 cells, and they are unique among iNKT cells to express the heparan sulfate proteoglycan CD138 and the trans...

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Detalles Bibliográficos
Autores principales: Luo, Shunqun, Kwon, Juntae, Crossman, Assiatu, Park, Pyong Woo, Park, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492317/
https://www.ncbi.nlm.nih.gov/pubmed/34549726
http://dx.doi.org/10.1172/jci.insight.148038