SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8

The inflammatory and IFN pathways of innate immunity play a key role in the resistance and pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2–associated molecular patterns (SAMPs) remain to be completely defined. Here, we identified single-stranded RNA (ssRNA) fragmen...

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Detalles Bibliográficos
Autores principales: Salvi, Valentina, Nguyen, Hoang Oanh, Sozio, Francesca, Schioppa, Tiziana, Gaudenzi, Carolina, Laffranchi, Mattia, Scapini, Patrizia, Passari, Mauro, Barbazza, Ilaria, Tiberio, Laura, Tamassia, Nicola, Garlanda, Cecilia, Del Prete, Annalisa, Cassatella, Marco A., Mantovani, Alberto, Sozzani, Silvano, Bosisio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492321/
https://www.ncbi.nlm.nih.gov/pubmed/34375313
http://dx.doi.org/10.1172/jci.insight.150542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492321/
https://www.ncbi.nlm.nih.gov/pubmed/34375313
http://dx.doi.org/10.1172/jci.insight.150542

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