Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells

Glioblastoma (GBM) is characterized by an aberrant yet druggable epigenetic landscape. One major family of epigenetic regulators, the histone deacetylases (HDACs), are considered promising therapeutic targets for GBM due to their repressive influences on transcription. Although HDACs share redundant...

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Detalles Bibliográficos
Autores principales: Lo Cascio, Costanza, McNamara, James B., Melendez, Ernesto L., Lewis, Erika M., Dufault, Matthew E., Sanai, Nader, Plaisier, Christopher L., Mehta, Shwetal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492336/
https://www.ncbi.nlm.nih.gov/pubmed/34494550
http://dx.doi.org/10.1172/jci.insight.149232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492336/
https://www.ncbi.nlm.nih.gov/pubmed/34494550
http://dx.doi.org/10.1172/jci.insight.149232

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