SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in high-grade serous ovarian cancer

Large independent analyses on cancer cell lines followed by functional studies have identified Schlafen 11 (SLFN11), a putative helicase, as the strongest predictor of sensitivity to DNA-damaging agents (DDAs), including platinum. However, its role as a prognostic biomarker is undefined, partially d...

Descripción completa

Detalles Bibliográficos
Autores principales: Winkler, Claudia, King, Matthew, Berthe, Julie, Ferraioli, Domenico, Garuti, Anna, Grillo, Federica, Rodriguez-Canales, Jaime, Ferrando, Lorenzo, Chopin, Nicolas, Ray-Coquard, Isabelle, Delpuech, Oona, Bedognetti, Davide, Ballestrero, Alberto, Leo, Elisabetta, Zoppoli, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492341/
https://www.ncbi.nlm.nih.gov/pubmed/34549724
http://dx.doi.org/10.1172/jci.insight.146098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492341/
https://www.ncbi.nlm.nih.gov/pubmed/34549724
http://dx.doi.org/10.1172/jci.insight.146098

Ejemplares similares