Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin)

Glioblastoma is a highly malignant brain tumor with no curative treatment options, and immune checkpoint blockade has not yet shown major impact. We hypothesized that drugs targeting mitosis might affect the tumor microenvironment and sensitize cancer cells to immunotherapy. We used 2 glioblastoma m...

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Detalles Bibliográficos
Autores principales: Genoud, Vassilis, Espinoza, Felipe I., Marinari, Eliana, Rochemont, Viviane, Dietrich, Pierre-Yves, McSheehy, Paul, Bachmann, Felix, Lane, Heidi A., Walker, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492343/
https://www.ncbi.nlm.nih.gov/pubmed/34403371
http://dx.doi.org/10.1172/jci.insight.142980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492343/
https://www.ncbi.nlm.nih.gov/pubmed/34403371
http://dx.doi.org/10.1172/jci.insight.142980

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