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Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma

BACKGROUND: Targeted arterial infusion of verapamil combined with chemotherapy (TVCC) is an effective clinical interventional therapy for esophageal squamous cell carcinoma (ESCC), but multidrug resistance (MDR) remains the major cause of relapse or poor prognosis, and the underlying molecular mecha...

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Detalles Bibliográficos
Autores principales: Min, Qingjie, Wang, Yan, Wu, Qingnan, Li, Xianfeng, Teng, Huajing, Fan, Jiawen, Cao, Yiren, Fan, Pingsheng, Zhan, Qimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492345/
https://www.ncbi.nlm.nih.gov/pubmed/34494553
http://dx.doi.org/10.1172/jci.insight.150203