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Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma
BACKGROUND: Targeted arterial infusion of verapamil combined with chemotherapy (TVCC) is an effective clinical interventional therapy for esophageal squamous cell carcinoma (ESCC), but multidrug resistance (MDR) remains the major cause of relapse or poor prognosis, and the underlying molecular mecha...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492345/ https://www.ncbi.nlm.nih.gov/pubmed/34494553 http://dx.doi.org/10.1172/jci.insight.150203 |