Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration

Haematopoietic stem cells (HSCs) are normally quiescent, but have evolved mechanisms to respond to stress. Here, we evaluate haematopoietic regeneration induced by chemotherapy. We detect robust chromatin reorganization followed by increased transcription of transposable elements (TEs) during early...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Clapes, Thomas, Polyzou, Aikaterini, Prater, Pia, Sagar, Morales-Hernández, Antonio, Ferrarini, Mariana Galvao, Kehrer, Natalie, Lefkopoulos, Stylianos, Bergo, Veronica, Hummel, Barbara, Obier, Nadine, Maticzka, Daniel, Bridgeman, Anne, Herman, Josip S., Ilik, Ibrahim, Klaeylé, Lhéanna, Rehwinkel, Jan, McKinney-Freeman, Shannon, Backofen, Rolf, Akhtar, Asifa, Cabezas-Wallscheid, Nina, Sawarkar, Ritwick, Rebollo, Rita, Grün, Dominic, Trompouki, Eirini
বিন্যাস: Online প্রবন্ধ পাঠ‍্য
ভাষা:English
প্রকাশিত: Nature Publishing Group UK 2021
বিষয়গুলি:
Article
অনলাইন ব্যবহার করুন:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492473/
https://www.ncbi.nlm.nih.gov/pubmed/34253898
http://dx.doi.org/10.1038/s41556-021-00707-9

আন্তর্জাল

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492473/
https://www.ncbi.nlm.nih.gov/pubmed/34253898
http://dx.doi.org/10.1038/s41556-021-00707-9

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