Cargando…

The application of cytokeratin-18 as a biomarker for drug-induced liver injury

Drug-induced liver injury (DILI) is a frequent and dangerous adverse effect faced during preclinical and clinical drug therapy. DILI is a leading cause of candidate drug attrition, withdrawal and in clinic, is the primary cause of acute liver failure. Traditional diagnostic markers for DILI include...

Descripción completa

Detalles Bibliográficos
Autores principales: Korver, Samantha, Bowen, Joanne, Pearson, Kara, Gonzalez, Raymond J., French, Neil, Park, Kevin, Jenkins, Rosalind, Goldring, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492595/
https://www.ncbi.nlm.nih.gov/pubmed/34322741
http://dx.doi.org/10.1007/s00204-021-03121-0