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The application of cytokeratin-18 as a biomarker for drug-induced liver injury
Drug-induced liver injury (DILI) is a frequent and dangerous adverse effect faced during preclinical and clinical drug therapy. DILI is a leading cause of candidate drug attrition, withdrawal and in clinic, is the primary cause of acute liver failure. Traditional diagnostic markers for DILI include...
Autores principales: | Korver, Samantha, Bowen, Joanne, Pearson, Kara, Gonzalez, Raymond J., French, Neil, Park, Kevin, Jenkins, Rosalind, Goldring, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492595/ https://www.ncbi.nlm.nih.gov/pubmed/34322741 http://dx.doi.org/10.1007/s00204-021-03121-0 |
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