The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner

The rapid, global dispersion of SARS-CoV-2 has led to the emergence of a diverse range of variants. Here, we describe how the mutational landscape of SARS-CoV-2 has shaped HLA-restricted T cell immunity at the population level during the first year of the pandemic. We analyzed a total of 330,246 hig...

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Detalles Bibliográficos
Autores principales: Hamelin, David J., Fournelle, Dominique, Grenier, Jean-Christophe, Schockaert, Jana, Kovalchik, Kevin A., Kubiniok, Peter, Mostefai, Fatima, Duquette, Jérôme D., Saab, Frederic, Sirois, Isabelle, Smith, Martin A., Pattijn, Sofie, Soudeyns, Hugo, Decaluwe, Hélène, Hussin, Julie, Caron, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492600/
https://www.ncbi.nlm.nih.gov/pubmed/34637888
http://dx.doi.org/10.1016/j.cels.2021.09.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492600/
https://www.ncbi.nlm.nih.gov/pubmed/34637888
http://dx.doi.org/10.1016/j.cels.2021.09.013

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