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Stress hormones promote DNA damage in human oral keratinocytes

Chronic stress increases the systemic levels of stress hormones norepinephrine and cortisol. As well as tobacco-specific carcinogen NNK (4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone), they can induce expressive DNA damage contributing to the cancer development. However, it is unknown whether stres...

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Detalles Bibliográficos
Autores principales: Valente, Vitor Bonetti, de Melo Cardoso, Diovana, Kayahara, Giseli Mitsuy, Nunes, Giovana Barros, Tjioe, Kellen Cristine, Biasoli, Éder Ricardo, Miyahara, Glauco Issamu, Oliveira, Sandra Helena Penha, Mingoti, Gisele Zoccal, Bernabé, Daniel Galera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492616/
https://www.ncbi.nlm.nih.gov/pubmed/34611221
http://dx.doi.org/10.1038/s41598-021-99224-w