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Concentration of Na(+)-taurocholate-cotransporting polypeptide expressed after in vitro-transcribed mRNA transfection determines susceptibility of hepatoma cells for hepatitis B virus

Infection of hepatocytes by hepatitis B virus (HBV) depends on surface expression of its receptor Na(+)-taurocholate-cotransporting polypeptide (NTCP), but sufficient NTCP expression is lacking in most cell lines. NTCP can be introduced by plasmid transfection or transduction by viral vectors to ren...

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Detalles Bibliográficos
Autores principales:	Oswald, Andreas, Chakraborty, Anindita, Ni, Yi, Wettengel, Jochen M., Urban, Stephan, Protzer, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492621/ https://www.ncbi.nlm.nih.gov/pubmed/34611272 http://dx.doi.org/10.1038/s41598-021-99263-3

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