Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington’s disease

Aggregation of proteins is a prominent hallmark of virtually all neurodegenerative disorders including Alzheimer’s, Parkinson’s and Huntington’s diseases. Little progress has been made in their treatment to slow or prevent the formation of aggregates by post-translational modification and regulation...

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Detalles Bibliográficos
Autores principales: Nedosekin, Dmitry A., Chen, TsungYen, Ayyadevara, Srinivas, Zharov, Vladimir P., Shmookler Reis, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492664/
https://www.ncbi.nlm.nih.gov/pubmed/34611196
http://dx.doi.org/10.1038/s41598-021-98661-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492664/
https://www.ncbi.nlm.nih.gov/pubmed/34611196
http://dx.doi.org/10.1038/s41598-021-98661-x

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