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Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington’s disease
Aggregation of proteins is a prominent hallmark of virtually all neurodegenerative disorders including Alzheimer’s, Parkinson’s and Huntington’s diseases. Little progress has been made in their treatment to slow or prevent the formation of aggregates by post-translational modification and regulation...
Autores principales: | Nedosekin, Dmitry A., Chen, TsungYen, Ayyadevara, Srinivas, Zharov, Vladimir P., Shmookler Reis, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492664/ https://www.ncbi.nlm.nih.gov/pubmed/34611196 http://dx.doi.org/10.1038/s41598-021-98661-x |
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