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The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway

Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into all blood cell lineages. Yet, the mechanistic basis for HSC development remains largely unknown. In this study, we characterized a zebrafish smu471 mutant with hematopoietic...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Wu, Mei, Li, Jing, Meng, Ping, Chen, Jiakui, Huang, Zhibin, Xu, Jin, Wen, Zilong, Zhang, Wenqing, Zhang, Yiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492694/
https://www.ncbi.nlm.nih.gov/pubmed/34611130
http://dx.doi.org/10.1038/s41419-021-04215-4