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The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into all blood cell lineages. Yet, the mechanistic basis for HSC development remains largely unknown. In this study, we characterized a zebrafish smu471 mutant with hematopoietic...
Autores principales: | Zhao, Yan, Wu, Mei, Li, Jing, Meng, Ping, Chen, Jiakui, Huang, Zhibin, Xu, Jin, Wen, Zilong, Zhang, Wenqing, Zhang, Yiyue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492694/ https://www.ncbi.nlm.nih.gov/pubmed/34611130 http://dx.doi.org/10.1038/s41419-021-04215-4 |
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