MRTF-A-NF-κB/p65 axis-mediated PDL1 transcription and expression contributes to immune evasion of non-small-cell lung cancer via TGF-β

PD-L1 is abnormally regulated in many cancers and is critical for immune escape. Fully understanding the regulation of PD-L1 expression is vital for improving the clinical efficacy of relevant anticancer agents. TGF-β plays an important role in the low reactivity of PD-1/PD-L1 antibody immunotherapy...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Fu, Qi, Xin, Zhang, Aotong, Sui, Fanfan, Wang, Xuemin, Proud, Christopher G., Lin, Cunzhi, Fan, Xinglong, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492728/
https://www.ncbi.nlm.nih.gov/pubmed/34548615
http://dx.doi.org/10.1038/s12276-021-00670-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492728/
https://www.ncbi.nlm.nih.gov/pubmed/34548615
http://dx.doi.org/10.1038/s12276-021-00670-3

Ejemplares similares