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Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells

Although functional interplay between intestinal microbiota and distant sites beyond the gut has been identified, the influence of microbiota-derived metabolites on hematopoietic stem cells (HSCs) remains unclear. This study investigated the role of microbiota-derived lactate in hematopoiesis using...

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Detalles Bibliográficos
Autores principales: Lee, Yong-Soo, Kim, Tae-Young, Kim, Yeji, Kim, Seungil, Lee, Su-Hyun, Seo, Sang-Uk, Zhou, Bo O., Eunju, O., Kim, Kwang Soon, Kweon, Mi-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492757/
https://www.ncbi.nlm.nih.gov/pubmed/34497346
http://dx.doi.org/10.1038/s12276-021-00667-y