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Aberrantly reduced expression of miR-342-5p contributes to CCND1-associated chronic myeloid leukemia progression and imatinib resistance

Chronic myeloid leukemia (CML) is a myeloproliferative disorder associated with the Philadelphia chromosome, and the current standard of care is the use of tyrosine kinase inhibitors (TKI). However, some patients will not achieve a molecular response and may progress to blast crisis, and the underly...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Ying, Lai, Hsing-Fan, Huang, Tzu-Chuan, Chen, Yu-Guang, Ye, Ren-Hua, Chang, Ping-Ying, Lai, Shiue-Wei, Chen, Yeu-Chin, Lee, Cho-Hao, Liu, Wei-Nung, Dai, Ming-Shen, Chen, Jia-Hong, Ho, Ching-Liang, Chiu, Yi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492784/
https://www.ncbi.nlm.nih.gov/pubmed/34611140
http://dx.doi.org/10.1038/s41419-021-04209-2