Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence

Senescence in placenta/fetal membranes is a normal phenomenon linked to term parturition. However, excessive senescence which may be induced by telomere attrition, has been associated with preeclampsia (PE). We hypothesized that the telomerase complex in peripheral blood mononuclear cells (PBMC) and...

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Detalles Bibliográficos
Autores principales: Lekva, Tove, Roland, Marie Cecilie Paasche, Estensen, Mette E., Norwitz, Errol R., Tilburgs, Tamara, Henriksen, Tore, Bollerslev, Jens, Normann, Kjersti R., Magnus, Per, Olstad, Ole Kristoffer, Aukrust, Pål, Ueland, Thor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492805/
https://www.ncbi.nlm.nih.gov/pubmed/34611223
http://dx.doi.org/10.1038/s41598-021-99140-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492805/
https://www.ncbi.nlm.nih.gov/pubmed/34611223
http://dx.doi.org/10.1038/s41598-021-99140-z

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