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Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Senescence in placenta/fetal membranes is a normal phenomenon linked to term parturition. However, excessive senescence which may be induced by telomere attrition, has been associated with preeclampsia (PE). We hypothesized that the telomerase complex in peripheral blood mononuclear cells (PBMC) and...
Autores principales: | Lekva, Tove, Roland, Marie Cecilie Paasche, Estensen, Mette E., Norwitz, Errol R., Tilburgs, Tamara, Henriksen, Tore, Bollerslev, Jens, Normann, Kjersti R., Magnus, Per, Olstad, Ole Kristoffer, Aukrust, Pål, Ueland, Thor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492805/ https://www.ncbi.nlm.nih.gov/pubmed/34611223 http://dx.doi.org/10.1038/s41598-021-99140-z |
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