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Tau and TDP-43 synergy: a novel therapeutic target for sporadic late-onset Alzheimer’s disease
Alzheimer’s disease (AD) is traditionally defined by the presence of two types of protein aggregates in the brain: amyloid plaques comprised of the protein amyloid-β (Aβ) and neurofibrillary tangles containing the protein tau. However, a large proportion (up to 57%) of AD patients also have TDP-43 a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492812/ https://www.ncbi.nlm.nih.gov/pubmed/34185246 http://dx.doi.org/10.1007/s11357-021-00407-0 |