Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice

How the heat shock axis, repair pathways, and proteostasis impact the rate of aging is not fully understood. Recent reports indicate that normal aging leads to a 50% change in several regulatory elements of the heat shock axis. Most notably is the age-dependent enhancement of inhibitory signals asso...

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Detalles Bibliográficos
Autores principales: Trivedi, Rachana, Knopf, Bailey, Tripathi, Jitendra Kumar, Rakoczy, Shar, Manocha, Gunjan D., Brown-Borg, Holly, Jurivich, Donald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492860/
https://www.ncbi.nlm.nih.gov/pubmed/33846884
http://dx.doi.org/10.1007/s11357-021-00362-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492860/
https://www.ncbi.nlm.nih.gov/pubmed/33846884
http://dx.doi.org/10.1007/s11357-021-00362-w

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