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Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair

Stem cell-based therapies with clinical applications require millions of cells. Therefore, repeated subculture is essential for cellular expansion, which is often complicated by replicative senescence. Cellular senescence contributes to reduced stem cell regenerative potential as it inhibits stem ce...

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Detalles Bibliográficos
Autores principales: Park, Ji Hye, Kim, Hyeok, Moon, Hyung Ryong, Park, Bong-Woo, Park, Jae-Hyun, Sim, Woo-Sup, Kim, Jin-Ju, Lim, Hye Ji, Kim, Yeon-Ju, Ji, Seung Taek, Jang, Woong Bi, Rethineswaran, Vinoth Kumar, Van, Le Thi Hong, Giang, Ly Thanh Truong, Yun, Jisoo, Ha, Jong Seong, Ban, Kiwon, Chung, Hae Young, Baek, Sang Hong, Park, Hun-Jun, Kwon, Sang-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492872/
https://www.ncbi.nlm.nih.gov/pubmed/34584195
http://dx.doi.org/10.1038/s12276-021-00676-x